http://www.clinical-depression.co.uk/half_life.htm
Seroxat/paroxetine half life = 21 to 26 hours,
Efexor/venlafaxine half life = 5 (5 to 11) hours
Venlafaxine in doses up to 150mg is an SSRI. Over 150 mg it also inhibitsnoradrenaline reuptake. Duloxetine is a potent serotonin reuptake inhibitor butnot selective to the serotonin system
You can access this file at the URL:http://groups.yahoo.com/group/SSRI-Crusaders/files/Healy_Withdrawal_june_09.pdf
Complaint Allegations:
http://bobfiddaman.blogspot.com/2011/02/paxil-withdrawal-reactions-class-action.html
1) The lawsuit further alleges that Paxil is a short "half life" drug which means it leaves
the body at a relatively fast rate. GSK uses this feature to distinguish it from its
competitors alleging that, as a result, it has a shorter
duration of adverse events, decreased drug accumulation over time, better management
of sexual dysfunction, and reduction of time to establish steady state drug regimen. The
great disadvantage of a short half life
substance, however, is that it is more addictive, has a greater tendency to induce
physical and psychological dependency, and causes withdrawal reactions. While these
characteristics of "half life" substances have been well known among Defendant and
psychopharmacologists, such information is not generally known by general practice
physicians or even psychiatrists.
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