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Wednesday 25 March 2009

If Clozapine kills 5.6 times more on 238 times less scripts than Seroxat - it must be 1300 times more dangerous

CLOZAPINE Total number of ADR reports: 11560 Total number of fatal ADR reports: 935Response to Download Drug Analysis Prints (DAPs)http://www.mhra.gov.uk/home/groups/public/documents/sentineldocum


Seroxat/ParoxetineTotal number of ADR reports: 10369 Total number of fatal ADR reports: 166
http://www.mhra.gov.uk/home/groups/public/documents/sentineldocuments/dap_1235564897002.pdfTotal number of ADR reports: 10369 Total number of fatal ADR reports: 166


Drug preparations, dressings and appliances listed alphabetically within British National Formulary classifications England 2007Seroxat_Tab 10mg 3 19.6 18.1 285.0 647.7 1 14.53 0.44 33.03Seroxat_Tab 20mg 3 37.2 0.0 673.3 1,529.0 1 18.08 0.44 41.06Seroxat_Tab 30mg 3 10.6 0.0 318.5 412.2 1 30.14 0.77 39.02Total for chemical entity : Paroxetine Hydrochloride 1,765.9 57.4 15,552.6 8.81see page 122 / 619http://www.ic.nhs.uk/webfiles/publications/PCA%20publication/PCA%202007%20complete%20V2.pdf




about 7400 Clozapine scripts in England 2007 for a drug that kills 1 per week
seehttp://www.ic.nhs.uk/webfiles/publications/PCA%20publication/PCA%202007%20complete%20V2.pdfpage 111 / 619Clozaril_Tab 100mg 3 2.5 1.8 214.7 244.4 1 85.59 0.88 97.40Clozaril_Tab 25mg 3 1.6 1.1 22.7 102.2 1 14.57 0.22 65.68Denzapine_Tab 100mg 3 1.2 1.0 84.1 95.5 1 70.53 0.88 80.15Denzapine_Tab 25mg 3 0.6 0.5 8.6 38.9 1 13.46 0.22 61.12Zaponex_Tab 100mg 3 0.9 0.8 21.3 33.2 1 24.97 0.64 38.90Zaponex_Tab 25mg 3 0.7 0.6 3.5 16.5 1 5.35 0.21 24.94Total for chemical entity : Clozapine 7.4 6.0 354.9 47.91

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