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Tuesday, 29 November 2011

SSRI withdrawal related to half life - means SEROXAT is NOT worst SSRI - FIDDAMAN

4. New evidence relevant to management of withdrawal reactions


http://bobfiddaman.blogspot.com/2011/11/mhra-meeting-to-discuss-awareness-and.html

Prof Healy was not aware of any new evidence relevant to the management of withdrawal reactions. When asked if he had a view on the size of the problem of serious and prolonged withdrawal reactions with SSRIs, Prof Healy said that this was not possible to measure. Prof Healy said that while the propensity of an SSRI to cause withdrawal reactions was often thought to be only related to the half-life of the drug, this seemed unlikely to be the case – it could also be related to the potency of
the different drugs at the serotonin reuptake site. The lack of understanding of the problem contributes to a lack of effective solutions.









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