The agency said it had looked at the evidence from a number of studies of fluoxetine, the active ingredient in Prozac, and concluded that it could double the background rate of congenital heart defects.
http://bobfiddaman.blogspot.com/2010/03/pregnant-women-warned-over-prozac-risk.html
About one in 100 babies are typically born with a problem such as a heart murmur, hole in the heart or other problem with the organ’s structure or rhythm.
But the MHRA estimates this rate increases to almost two in 100 pregnancies among women prescribed fluoxetine, which is a similar rate to another common antidepressant, Seroxat (paroxetine).
The drugs are part of a group known as selective serotonin reuptake inhibitors (SSRIs), which are not recommended to be taken during pregnancy because of the risk of withdrawal symptoms in the developing baby.
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