SEROXAT SUFFERERS - STAND UP AND BE COUNTED

Most Seroxat clients dropped because they were taking other drugs in conjunction with their paroxetine

2009-12-10T10:00:00.005Z

The reason why there are only 600 or so claimaints left in the UK Seroxat class action against GSK is because many cases were dropped because of doctors prescribing other drugs in conjunction with Seroxat. I know personally of many people who have been dropped from the class action because of this and other factors...

Oh and by the way, Janice Simmons of the seroxatusersgroup met with UK prime minister Gordon Brown at downing street a few days ago. Bear in mind that there is currently a 4 year long investigation into the conduct of GSK regarding Seroxat prescribing to children/suppression of negative clinical data etc..

http://fiddaman.blogspot.com/2007/11/honourable-members.html

But bear in mind also that JP Garnier( GSK CEO) is also on "Gordon Browns Business Council"...
Also worthy of thought is what GSK means to the UK economy..
It is virtually an English institution with its roots firmly cemented in UK research/developement/sponsorship/employment etc..
It is the UK's Major Pharma Cash Cow..
And it is prized very much as being such...

Will be interesting when more info on this meeting begins to bear fruit...
But i have a feeling that the UK seroxat scandal is a can of worms which has been eating its way right through the core of UK politics for quite some time now...
And when something has become that rotten..
Most people won't touch it...

Posted by truthman30 at December 2, 2007 04:24 PM

http://209.85.229.132/search?q=cache:17IP6JGo25kJ:www.furiousseasons.com/movabletype/mt-comments.cgi%3Fentry_id%3D1151+seroxat+group+litigation&cd=10&hl=en&ct=clnk

Why is there only 600 litigants when the Seroxat User Group claimed it had 10,000 members - asks Will @ Furious Seasons

2009-12-10T09:40:00.001Z

I wonder why there were only 600 clients when it was very much the case that the "Online Seroxat Support Group" & "seroxatUSERSgroup" claimed they represented 10.000 + members.

see- http://www.seroxatusergroup.org.uk/EMEA%20minutes%20April%202004.pdf

I note that both Derek Scott of OSSG & Janice Simmons of sUg both attended the EMEA meeting of April 2004

Posted by Will at November 25, 2007 09:12 AM

http://209.85.229.132/search?q=cache:17IP6JGo25kJ:www.furiousseasons.com/movabletype/mt-comments.cgi%3Fentry_id%3D1151+seroxat+group+litigation&cd=10&hl=en&ct=clnk

Result of Seroxat placebo control trial on personality - note this trial was not funded by GSK

2009-12-09T11:34:00.003Z

Results Patients who took paroxetine reported greater personality change than placebo patients, even after controlling for depression improvement (neuroticism, P < .001; extraversion, P = .002). The advantage of paroxetine over placebo in antidepressant efficacy was no longer significant after controlling for change in neuroticism (P = .46) or extraversion (P = .14). Patients taking paroxetine reported 6.8 times as much change on neuroticism and 3.5 times as much change on extraversion as placebo patients matched for depression improvement. Although placebo patients exhibited substantial depression improvement (Hamilton Rating Scale for Depression score, ¨C1.2 SD, P < .001), they reported little change on neuroticism (¨C0.18 SD, P = .08) or extraversion (0.08 SD, P = .50). Cognitive therapy produced greater personality change than placebo (P .01); but its advantage on neuroticism was no longer significant after controlling for depression (P = .14). Neuroticism reduction during treatment predicted lower relapse rates among paroxetine responders (P = .003) but not among cognitive therapy responders (P = .86).

http://groups.yahoo.com/group/uksurvivors/message/52420

http://archpsyc.ama-assn.org/cgi/content/abstract/66/12/1322

uksurvivors : Message: Personality Change During Depression Treatment - placebo cont trial

2009-12-09T11:33:00.001Z

uksurvivors : Message: Personality Change During Depression Treatment - placebo cont trial: "Personality Change During Depression Treatment
A Placebo-Controlled Trial"

http://archpsyc.ama-assn.org/cgi/content/abstract/66/12/1322

uksurvivors : Message: Seroxat personality study NOT funded by GSK .....how interesting

2009-12-09T11:09:00.000Z

uksurvivors : Message: Seroxat personality study NOT funded by GSK .....how interesting

Seroxat lawyers media machine makes matters worse for consumers of all other brands of SSRI

2009-12-08T20:44:00.002Z

Steph & others reading your attention is drawn to

http://health.groups.yahoo.com/group/SSRI-Crusaders/message/34746

http://coventryuniversity.podbean.com/2007/11/01/one-woman-a-multinational-and-a-victory-shelley-jofre-panorama/

which is a podcast of Shelley Jofre speaking at Sheffield University date Nov 2007

from the transcript please note -

4 .30 in Ed says - lets look at antidepressant story

4 45 Jofre says although problems with whole class of antidepressants we (bbc) decided to concentrate on Seroxat Why we narrowed down on Seroxat 1 because it was made by GSK 2 all the drugs in class cause suicidal thinking on dose change 3 Seroxat had a unique problem of withdrawal BECAUSE IT WAS LONGER ACTING … we decided to focus research into this drug

So here we have it straight from the horses mouth that not only did the BBC know that there was a class wide problem with SSRI, they chose despite this knowledge, to focus research on seroxat !

Quite how the UK lawyers media machine can be seen as a help, to those seeking to bring awareness about all psychiatric drugs, when they, in the face of there own knowledge, decided to ignore the bulk of the problem (all drugs in class), is beyond comprehension.

The BBC is a public sector broadcaster responsible to all like me, who have no choice but to pay a tax (broadcasting licence) to them. So it comes with a sense of total bewilderment to learn from Jofre, that not only did Panorama take 8 months to make, but that the UK litigation lawyer was involved throughout the process!!

read transcript

6.00 in - 40 min Panorama film took Shelley Jofre 8 months to make

&

7.30 We were talking to the lawyer the whole way through production

So Steph here was prime opportunity to bring awareness about all SSRI's & the whole thing was ceeded to the only persons who will benefit ....the UK lawyers

So lets look again at what Jofre said @ 6:10

6.10 in - It's not something you do lightly WE WERE TAKING ON the worlds second largest drug company

Quite frankly Steph that is not something the BBC has a remit to do.

It has become partisan.

Remember whilst the BBC is fighting Hugh James' wars for them they (BBC) are by their own admission failing to help people who take brands other than Paxil/Seroxat .............i.e. the majority of the consumers.

.

The net result which is easy to show (from national statistics) is a dissaster.

BBC & Jofre should hang their head in shame.

Now I realise this won't lie easy with those of you who have met Jofre in person, so for those that know her, I suggest you invite her & her producer at Panorama to join the debate here at SSRIcrusaders.

I'll not hold my breath, as with the UK seroaxt caucus I don't expect that they are capable of self reflection.

The UK now has a runaway problem with several brands of antidepressants a regulator that is bogged down by seroxat "created issues", one that has failed to do its job to the detriment of anyone who takes an antidepressant NOT made by GSK

And you think this helps Steph?

Jeremy

(( note in writing this post I am not in anyway attempting to defend GSK ))

BBC admits it knew there was a problem with the entire class of SSRI's, yet THEY targeted GSK product Seroxat !

2009-12-02T17:34:00.007Z

2.30 in Jofre says - ” read a little bit in news paper about patients complaints” year 2000 about ” Seroxat difficult to withdraw from” .. Jofre found it intriguing Jofre had only just started working on Panorama at that stage
3.30 in ” Jofre calls SSRI’s “SELECTIVE Serotonin Reuptake Inhibitors”
4.14 Jofre knew little of how the pharmcutical industry worked
4 .30 in Ed says - lets look at antidepressant story
4 45 Jofre says although problems with whole class of antidepressants we (bbc) decided to concentrate on Seroxat Why we narrowed down on Seroxat 1 because it was made by GSK 2 all the drugs in class cause suicidal thinking on dose change 3 Seroxat had a unique problem of withdrawal BECAUSE IT WAS LONGER ACTING … we decided to focus research into this drug
6.00 in - 40 min Panorama film took Shelley Jofre 8 months to make
6.10 in - It’s not something you do lightly WE WERE TAKING ON the worlds second largest drug company
7.30 We were talking to the lawyer the whole way through production
9.30 in - Jofre says “we took a punt” on Dr David Healy

Anon Commenter is missing the point - MOST people, just weeks after cold turkey withdrawal COULDN'T go to a concert, many struggle for months, some for years and some are permanently disabled! Others have killed themselves!

2009-12-02T16:56:00.021Z

http://209.85.229.132/search?sourceid=navclient-ff&ie=UTF-8&q=cache%3Ahttp%3A%2F%2Fstrangfordbryce.blogspot.com%2F2009%2F12%2Fharassment-act-1997.html

http://strangfordbryce.blogspot.com/

Protection from Harassment Act - re blogs created to prevent or detect a crime

2009-12-02T13:46:00.004Z

http://www.opsi.gov.uk/acts/acts1997/ukpga_19970040_en_1

1 Prohibition of harassment
(1) A person must not pursue a course of conduct—
(a) which amounts to harassment of another, and
(b) which he knows or ought to know amounts to harassment of the other.

(2) For the purposes of this section, the person whose course of conduct is in question ought to know that it amounts to harassment of another if a reasonable person in possession of the same information would think the course of conduct amounted to harassment of the other.

(3) Subsection (1) does not apply to a course of conduct if the person who pursued it shows—
(a) that it was pursued for the purpose of preventing or detecting crime,
(b) that it was pursued under any enactment or rule of law or to comply with any condition or requirement imposed by any person under any enactment, or
(c) that in the particular circumstances the pursuit of the course of conduct was reasonable.

ProzacAwareness : Message: World Exclusive - Fiddaman had no lasting effects after going cold turkey

2009-12-02T11:33:00.001Z

ProzacAwareness : Message: World Exclusive - Fiddaman had no lasting effects after going cold turkey

criticalpsychiatry : Message: World Exclusive - Fiddaman had no lasting effects after going cold turkey

2009-12-02T11:32:00.001Z

criticalpsychiatry : Message: World Exclusive - Fiddaman had no lasting effects after going cold turkey

SSRI-Crusaders : Message: World Exclusive - Fiddaman had no lasting effects after going cold turkey

2009-12-02T11:30:00.000Z

SSRI-Crusaders : Message: World Exclusive - Fiddaman had no lasting effects after going cold turkey: "*** World Exclusive - Fiddaman had no lasting effects after going cold turkey & went to a gig 21 Apr 2004

http://www.bobfiddaman.blogspot.com/"

4+ weeks after starting cold turkey Bob Fiddaman promotes Casbah Club Gig @ Wrexham

2009-12-02T10:31:00.005Z

http://groups.google.com/group/uk.local.north-wales/browse_thread/thread/91af9370b3ef311/d1ae974b140b0c65?hl=en&ie=UTF-8&oe=UTF-8&q=fiddy+casbah+club&pli=1

4+ weeks after starting cold turkey Bob Fiddaman promotes upcoming Casbah Club Gig @ Wolverhampton

2009-12-02T10:22:00.002Z

http://groups.google.com/group/free.uk.talk.wolverhampton/browse_thread/thread/9753b32ec0b49cd7/eb8ee36b941ae2a9?hl=en&ie=UTF-8&oe=UTF-8&q=fiddy+casbah+club

So seven weeks after starting cold turkey Bob Fiddaman goes to The Robin 2 - The Midlands Premier 700 capacity live concert venue !!

2009-12-02T09:31:00.001Z

The Robin 2 - The Midlands Premier 700 capacity live concert venue

The Robin 2 is the Midlands premiere 700 capacity live concert venue. Situated in Bilston in the heart of the Black Country.

http://www.therobin.co.uk//

Bob Fiddaman's 22 Apr 2004 review of Casbah Club gig, which took place 21 Apr 2004 at the The Robin 2

2009-12-01T16:17:00.007Z

From: Robert Mann Date: Thursday, 22 April 2004, at 5:38 pm

There isn't many concerts that can leave one feeling completely satisfied - well not since the days of Acca Dacca and Big Country. But wait......... we have the Casbah Club, a five peice set of muso's who probably have a combined age nearing the 300 mark.

With a sense of great anticipation, after reviews on this board, I got into the spirit of things with my buddy Arun and met a few familiar faces. Was surprised to see so much merchandise on sale and even more suprised to see the Big Country wooly hats - only wish I would have bought more funds so I could have purchased one.

read on - http://www.bigcountry.co.uk/news/articleRead.php?id=18

http://209.85.229.132/search?q=cache:2kRcv9fSwn4J:www.bigcountry.co.uk/news/articleRead.php%3Fid%3D18+robert+mann+casbah+club&cd=3&hl=en&ct=clnk

*** Exclusive - what it was really like for Fiddaman a few weeks after withdrawing cold turkey

2009-12-01T16:11:00.004Z

http://www.bigcountry.co.uk/news/articleRead.php?id=18

So how was withdrawal for you Bob? - did you really suffer? - did you have real problems?

2009-12-01T12:01:00.001Z

Come back later & we will show you how Bob Fiddaman got on.

PANES case 4 & 5 - persistent pains in the legs 3 months after withdrawal,

2009-11-30T23:09:00.000Z

Mrs D., a 49 year old health professional was prescribed 20 mg paroxetine daily in April 2000 for a depressive disorder. This relieved the depression, but aftr three months the patient started to develop paresthesiae in the right hand, and some weeks later experienced her fingers being 'fumbly'. She visited her GP and complained that although her mood was satisfactory there were unpleasant side effects. He asked her to reduce the dose to 10 mg daily. Mrs D began to experience painful, restless legs at night and vivid dreams. The tingling in her hand spread into her body and head. After a week of the 10 mg dose the patient discontinued the paroxetine altogether in the belief that the paroxetine would be out of her system in a few days and her symptoms would subside. The symptoms however persisted. She took a week off work, but the following symptoms persisted for the next three months:

paraesthesiae in hands and feet spreading up arms and legs intermittently

stiffness in calf muscles

unsteadiness on her feet with wide gait

clumsy fingers

loose bowels

disinhibited mood

These symptoms appeared worst at the end of the day, following heavy physical work,and with even small amounts of alcohol. By December, four months after discontinuing the paroxetine most of the symptoms had reduced in severity to near normal.

Mrs E., a 48 year old woman was prescribed citalopram by her GP for eleven months. The indication for the prescription was chronic anxiety. For fifteen months folowing the discontinuation of this therapy she suffered headaches and dizziness. She also complained of a fluttering sensation across her scalp. To date there has been little improvement.

So how was withdrawal for you Bob ?

2009-11-30T23:01:00.003Z

http://bobfiddaman.com/custom/fiddy1.jpg

PANES case 3 - 8 months after withdrawal she still had myoclonic jerks

2009-11-30T23:00:00.000Z

Mrs C., a 29-year-old mother of one, became ill with depression when her son was aged eight months. She was suicidal and required hospital admission where she was started on fluoxetine 20 mg daily. The antidepressant worked well and her mood was restored within four weeks of admission. She was discharged home, but commented that her sleep was occasionally disturbed by bad dreams and she was aware of twitching in the bed. She was kept on the fluoxetine for a further twelve months and at outpatient reviews mentioned that her sleep was still occasionally disturbed by nocturnal twitching. She said that her husband had started to sleep separately, because he was 'tired of being kicked' in the middle of the night. The fluoxetine was discontinued eighteen months after the admission. Mrs C described no worsening of her mood and was euthymic and outpatient review. However, she was distressed to report that her nocturnal twitching, which took the form of sudden myoclonic jerks of her limbs, had actually worsened off fluoxetine. During the day these abnormal involuntary movements were less marked and more easily disguised, but nonetheless problematic for the patient. At follow-up eight months after discontinuation the untoward myoclonic jerks were continuing. There are no focal neurological signs or any features suggestive of progressive neurological disease, nor was there a family history of neurological disease.

So how was withdrawal for you Bob ?

2009-11-30T20:47:00.001Z

PANES case 2 - withdrawal over 6 weeks - paraesthesiae, dizziness, mild ataxia, and slurred speech continue for 12 months

2009-11-30T20:46:00.000Z

A 35-year-old man (Mr B) was prescribed paroxetine 30 mg daily for depression. The depression resolved and the paroxetine was continued at the same dose for two years. The medication was discontinued in a staged way, with reductions to 20, then 10 mg, managed over six weeks or so. Symptoms of withdrawal occurred throughout this period and comprised vivid nightmares, lability of mood, irritability, hypersexuality, episodic lightheadedness, episodic electric-shock like sensations, glove paraesthesiae, and ataxia. These symptoms ended two weeks after the withdrawal regime was finished. Nevertheless the patient continued to describe problems of an episodic nature well after the paroxetine had been discontinued. These episodes lasting hours to days at a time and comprised paraesthesiae, dizziness, mild ataxia, and slurred speech. These episodes have occurred intermittently throughout twelve months of follow-up during which time the patient has been drug-free. There are no focal neurological signs or any features suggestive of progressive neurological disease, nor was there a family history of neurological disease

So how was withdrawal for you Bob ?

2009-11-30T16:52:00.004Z

http://bobfiddaman.com/custom/fiddy1.jpg

PANES case 1 - just like Bob she was on dothiepin, then on to Seroxat - withdrawal due to dystonic reaction - 7 months later she still had dystonia

2009-11-30T16:51:00.000Z

Mrs A. a 29 year old married lady with a moderate depressive disorder was switched to paroxetine by her general practitioner after an initial prescription of dothiepin. She had found the tricyclic dothiepin too sedating and after a week or so of this medication requested a change. After two weeks on paroxetine 20 mg daily she was reviewed by a consultant psychiatrist who increased the dose to 40 mg daily. The patient suffered a dystonic reaction to the paroxetine that required physician review and admission, but apparently responded well to procyclidine. The paroxetine was discontinued. Unfortunately the dystonic reaction persisted off all medication and required further medical admission and the re-prescription of procyclidine. The depression continued unabated and a tricyclic was started with some improvement in mood. Seven months after the paroxetine had been stopped the tardive dystonia was noted to be present and to vary with anxiety levels, body posture, alertness, and emotional state.

http://priory.com/psych/panes.htm#Case1